New ‘spin freezing’ technique could enhance future mRNA vaccines

Ghent University has received funding from CEPI to explore whether a pioneering vaccine stabilisation technique could end the need for frozen storage of mRNA vaccines and support a fast and scaled-up response to future outbreaks in as little as 100 days.

Ghent University will receive up to US $1.9 million to test the performance of optimised mRNA vaccines, developed on the university’s specialised mRNA Galsomes platform, in preclinical models after ‘spin-freezing’ the vaccines. Pioneered by RheaVita, a spin-off company of Ghent University, spin-freezing is a novel alternative to the traditional freeze-drying method. The research will be supported by Flanders Institute for Biotechnology (VIB).